G20 is a forum for impotence over the global economy
n unhealthy battle has surfaced among policy makers this autumn, with the winner appearing to be the person who can describe the global economy in the most apocalyptic terms. Christine Lagarde, International Monetary Fund managing director, fired the … Read more on Financial Times
Donadoni: 'Impotence and shame'
The Ducali had never previously lost a Serie A game by more than a five-goal margin. “I had never lost 7-0 either in my career,” the Coach told Rai Sport. “These are games easy to comment on: we faced a great Juve side and we never turned up. “There is … Read more on Football Italia
Anti-impotence drugs seized
MANILA, Philippines—Customs authorities have seized a parcel containing anti-impotence drugs mailed from the United States. The parcel, which contained 268 blue-colored pills suspected to be sildenafil citrate—a drug used to treat erectile … Read more on Inquirer.net
Daily dose of Viagra to ease pain of cystitis
The results revealed that the women on Viagra felt less need to go to the loo, got up fewer times at night to urinate and had fewer complications, such as pain, than those on the dummy drug. Nearly two-thirds of those in the Viagra group reported a … Read more on Daily Mail
Phoenix man gets probation for selling fake Viagra
The Pfizer Corporation hired a private security company in April 2014 to help in the investigation of possible counterfeit Pfizer products being sold online. The security company purchased Viagra from a website and Pfizer determined the product was … Read more on YourWestValley.com
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There are hundreds of millions of males suffering from sexual dysfunction in the world, of which over 50 million are in China. Statistics indicates that more than 60% of males aged above 35 in China have sexual dysfunction of different degrees. About 50% of the causes of erectile dysfunction are organic, and 30% are psychological while 20% of them are organic and psychological at the same time. Erectile dysfunction can have severe psychological consequences as it can be tied to relationship difficulties and masculine selfimage generally. Consequently many pharmaceutical enterprises are very concerned about male sexual dysfunction drug market.
Sildenafil, developed by Pfizer Co., Ltd., was originally developed as a phosphodiesterase type 5 inhibitor (PDE5 inhibitor) to treat cardiovascular diseases. However, the medicine did not avail against the disease. In April 1991, the clinical research of sildenafil officially failed, but a side effect in the report attracted the researchers’ attention. They found that patients were unwilling to return the remaining medication after the trial. Through further investigation researchers discovered that the medication can improve the patients’ sexual life. Under the permission of Pfizer’s top management, experiment about sildenafil’s effect on penile corpus cavernosum smooth muscle was carried out. The medication (sildenafil produced by Pfizer with the trade name “Viagra”) was approved to the market by FDA on March 27, 1998, which soon became a worldfamous product of Pfizer Co., Ltd.
Besides erectile dysfunction, sildenafil is also useful for the prevention and treatment of highaltitude pulmonary edema and altitude sickness.
Neuropathic pain is caused by damage or pathological changes of nervous system. Its main features are dull pain, aestus and tingling. About 1% of people worldwide have neuropathic pain. Epileptic seizures are the result of excessive and abnormal cortical nerve cell activity in the brain. It is a group of longterm neurological disorders. As a chronic disease, epilepsy can seriously damage patients’ mental and physical health and become a huge burden for their families and the society. According to WHO, the global number of epilepsy patients is higher than 50 million and over 9 million of them are in China.
Pfizer Co., Ltd. submitted registration application for Pregabalin (produced by Pfizer with the trade name “Lyrica”) in the U.S. in 2003. In December 2004 pregabalin was approved by FDA to treat diabetic neuropathic pain and postherpetic neuralgia. It is the first drug approved to treat both the two diseases in the U.S.A. and in Europe. In June 2005, pregabalin was approved to be used in the adjuvant treatment of adults with partialonset seizures in epilepsy. After that, it was approved to treat generalized anxiety disorder and fibromyalgia syndrome successively. Time Magazine named pregabalin as one of the “Top 10 Medical Progress” in 2007. Total revenue of pregabalin is more than USD 20 billion. The global sales revenue of Lyrica was approximately USD 4.16 billion, increased by 13% YOY.
In 2010 Lyrica was approved to China. According to CRI’s market investigation, the sales revenue of Lyrica in Chinese sample hospital market grew over 100 times from 2010 to 2013. Due to Lyrica’s success, many pharmaceutical manufacturers in China begin to apply for pregabalin production. Chongqing Succeway Pharmaceutical Co., Ltd. received production license in 2013. Lyrica produced by Pfizer is expected to be the main product in Chinese market in recent years. However, its market share will decline in 2014 due to competition from relatively cheap homemade drugs.
ChinaMarketResearchReports.com (http://www.chinamarketresearchreports.com/ .) is an online database of market research reports offers in-depth analysis of over 5000 market segments. The library has syndicated reports by leading market research publishers across the globe and also offer customized market research reports for multiple industries.
Propecia is a prescription only medicine and currently costs around £40 per month, however this could reduce very substantially in the coming weeks. The price of the generic alternative to branded Viagra fell by about 90% when it’s patent expired last year. Now sildenafil (generic Viagra) is more freely available on the NHS, and the same may happen with Propecia.
“This is welcome news for men suffering from male pattern or hereditary hair loss. This treatment is usually not available on the NHS, the savings could be significant.”
A generic medicine is a medicine which is the same as a branded original, but is prescribed and supplied by its medical name, rather than its brand name.
Propecia is a brand name. The active ingredient of Propecia tablets is finasteride 1mg. Propecia tablets and finasteride 1mg tablets are medically the same.
The drug company Merck (MSD) held the original patent. The lower cost generic finasteride 1mg tablets are now being supplied by other drug companies, since Merck’s UK patent expired.
Why patent expiry matters
When a medicine comes off patent price can fall dramatically, as seen when Viagra (medical name sildenafil) came off-patent last year and prices plummeted within a week.
Men, who previously paid very high prices for Propecia, may be able to buy medically identical finasteride 1mg at lower prices in the coming weeks.
When a medicine is under patent it can only be sold legally by the patent holder – in the case of Propecia the pharmaceutical company Merck (MSD). This means the patent holder, which paid to develop the medicine in the first place, is free to market the medicine without competition from other pharmaceutical companies. The result is usually very high prices. When a patent expires other drug companies usually start to produce the same medicine, known as a generic copy. They then start to compete on price. As a result the cost to patients tends to fall.
How low will the price of Propecia / finasteride 1mg fall?
The cost to patients of a medicine depends on various factors; how much it costs to produce, how much demand there is, how many drug companies supply the same medicine, and how flexible the market is. Even when the wholesale supply price of a medicine falls, the price patients pay does not always fall by the same amount. Retail pharmacies may try not to pass on reduced supply costs to patients, and instead use falling wholesale prices to boost profits. If there is price competition between retailers, as there tends to be between online pharmacies and online clinics, price to patients usually falls in line with falls in wholesale supply costs, but not always.
At the moment (Oct 14th 2014) only two pharmaceutical companies, apart from Merck (MSD), are supplying finasteride 1mg tablets. These companies are Trent and Actavis. At the time of writing, both are offering their generic equivalent of Propecia at the same price; about 10% less than branded Propecia. Prices will hopefully fall further in the days and weeks to come as other pharma companies make generic versions available and the market adjusts.
The original patent holder, Merck (MSD) may reduce the price of Propecia, or start to market its own generic finasteride 1mg alongside branded Propecia.
Brand loyalty and peace of mind
Not all men who currently take Propecia will switch to generic finasteride 1mg, even if the price of Propecia remains high and generic finasteride is a lot cheaper. If a patient is happy with a particular brand of tablet, they often will not switch to a lower cost equivalent, even if they are reliably advised that one tablet is medically the same as the other. Whether or not they switch depends on how much they wish to economise, and all the other factors which keep people buying certain products at high prices when they do not have to.
Propecia/Finasteride 1mg tablets are taken daily to reduce hair loss in men, and can promote hair regrowth. Hair growth usually starts to improve after three months. Two thirds of men who take Propecia will benefit from renewed hair growth. Maximum benefit is seen after two years.
See Dr Fox hair loss pages for details. Dr Fox is one of the lowest cost suppliers of most medicines for both branded and generic versions.
Pfizer Stock Buyback Plan Just Too Large to Ignore — It Is on Viagra
A Pfizer Inc. (NYSE: PFE) press release on Thursday evening was honestly given the wrong title by the company's investor relations department. The new release titled “Pfizer Declares 26-Cent Fourth-Quarter 2014 Dividend” should have been named “Pfizer … Read more on 24/7 Wall St.
Viagra Could Be Good For Heart Health, Study Says
A blister pack containing Pfizer's 0.50mg Viagra tablets, produced by Pfizer Inc., is arranged for a photograph in London, U.K., on Friday, May 2, 2014. AstraZeneca Plc rejected Pfizer Inc.'s sweetened takeover proposal, saying the 63.1 billion-pound … Read more on Huffington Post
Viagra ads becoming more explicit
In the United States, where Viagra sales increased 3 percent in the second quarter, Pfizer probably won't face generic competition in this category until 2017, when a negotiated deal with Teva Pharmaceutical Industries will allow Teva to introduce a … Read more on Philly.com
The Managed WordPress Hosting service from Trent Studios, LLC, allows the business owner to focus on their business while Trent Studios keeps their website safe and secure. They can rest easier knowing that their WordPress website on Trent Studios’ dedicated server environment is secure, kept backed-up, and up-to-date with the latest software.
WordPress is a content management system and blogging platform. Think of WordPress as website-building software. It’s free and gets installed into the website. It’s not something that’s installed on a personal computer. The appearance of a WordPress website can be changed with what’s called a ‘theme’. The functionality of a WordPress website can be changed by installing plug-ins, such as a contact form plug-in, or a shopping cart plug-in.
Think of hosting as the place a website lives. It’s like the lot a house sits on.
The developers of WordPress, the theme, and any plug-ins installed, release updates from time to time that include new features or security patches. Those security patches are why it’s a good idea to keep a WordPress website kept up-to-date. But before the website is updated, it needs to be backed-up, in case something goes wrong.
There’s more to a secure WordPress site than just keeping software up-to-date. As part of Trent Studios’ Managed WordPress Hosting service, they also make changes to how WordPress gets installed and who, or what, can have access to it. For example, the first thing hackers do to gain access to a website is try to figure out where the log-in page is, and what the username and password is. The default log-in URL is somewebsite.com/wp-admin/. The folks at Trent Studios, LLC, simply change this to something different. They also use strong passwords. A few of the many things they do to secure a WordPress website are highlighted on their website at http://trentstudios.com/managed-wordpress-hosting/
If there’s been a breach to the website, they try to find out how the hacker got in and fix it, find and quarantine the injection, and evaluate what can be done to prevent that from happening again.
The reason security is so important is because hackers all around the world are looking for vulnerable websites they can hack into. If a WordPress website has a plug-in that has a known security vulnerability, hackers will find it eventually, and when they do, they may use it to send spam or replace the home page with a Viagra ad.
Just about everybody offers WordPress hosting. But not everybody offers Managed WordPress Hosting or goes to the length Trent Studios, LLC does to keep a WordPress safe and secure. Security is their primary concern.
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